PDRN Manufacturer | Private Label PDRN Skincare

Moe’s Group is a PDRN private-label manufacturer based in Chatsworth, California, and we hold the material in stock. We formulate, fill and label PDRN skincare under private label, white label and fully custom formulation, working with salmon PDRN and rose PDRN held in-house and further plant-derived sources available on request. This is a contract manufacturer’s hub for the ingredient, including the parts of the PDRN story that are less flattering than the marketing suggests.

Who manufactures PDRN skincare in the USA?

Moe’s Group does, at our own facility in Chatsworth, California. We are a private-label and custom-formulation cosmetics manufacturer holding both salmon PDRN and rose PDRN in stock, formulating in house rather than sourcing the active piece by piece for each project. A brand can arrive with a concept and leave with a bulk-produced, shelf-ready product formulated to spec, without switching partners between raw material and finished goods.

Can Moe’s Group manufacture PDRN products under private label?

Yes. We formulate, fill and label PDRN skincare under private label, white label or fully custom formulation, in essence, serum, ampoule, cream and sheet mask formats. Salmon PDRN and rose PDRN are held in stock, and our in-house chemists formulate to a brand’s source, concentration and format. Brands set their own MOQs and timelines.

Which PDRN sources do you stock?

Salmon PDRN and rose PDRN are in stock at the Chatsworth facility today. Salmon PDRN is the original and most widely recognised form of the ingredient, the source that made the category famous in K-beauty. Rose PDRN, derived from the stem cells of the Damascus rose, is the leading vegan, plant-based alternative, naturally rich in antioxidants and amino acids and a fit for fragrance-free and sensitive-skin lines. Beyond those two, we can source the other variants brands ask for most, including ginseng (Panax), rice and green tea PDRN. For a full side-by-side, see our comparison of salmon PDRN versus rose PDRN.

What does the PDRN research actually cover?

Less than the marketing implies, and it is worth being plain about it. The bulk of the published human work on PDRN concerns salmon-derived PDRN injected into the skin in a clinical setting – a different product, a different route into the body, and in most markets a different regulatory category from a cosmetic. The evidence for topical salmon PDRN is considerably thinner, and the evidence for topical vegan PDRN in humans is thinner still: as of mid-2025 there were no published human clinical trials on topical vegan PDRN at all. A brand can build a very good cosmetic on this ingredient. It cannot honestly borrow the injectable literature to describe what a serum does.

Is rose PDRN as effective as salmon PDRN?

Nobody can honestly say yes on the current evidence, and nobody can honestly say no either. What exists for plant-derived polynucleotides is preclinical – cell culture and tissue-model work – and it is source specific. Published work on ginseng-derived or peony-derived polynucleotides is not evidence for rose, rice or yeast-derived material, and it should not be cited as though it were. Choose rose PDRN because vegan positioning and a botanical story are right for your brand, not because you have been shown a study that was run on a different plant.

Which PDRN belongs in a vegan or cruelty-free line?

Rose PDRN, and this is the one decision in the category that is genuinely clear cut. Salmon PDRN is an animal-derived material extracted from fish milt, so it cannot sit in a vegan line, and it will be the wrong answer for brands working to certain religious dietary certifications or selling into markets where that matters. Rose PDRN is the straightforward substitute and suits fragrance-free and sensitive-skin formulas well. If your range is mixed, there is no reason you cannot run salmon PDRN in one line and rose PDRN in another from the same formulation partner.

How does PDRN appear on an ingredient list?

Usually not as the word PDRN. The INCI designation for cosmetic PDRN is typically sodium DNA, sometimes hydrolyzed DNA. Consumers looking for PDRN on a label will not find that phrase, which is why so many finished products carry it in the marketing copy on the front and sodium DNA in the ingredient list on the back. For plant-derived materials the naming is less settled and varies by supplier, so ask for the exact INCI on the raw material spec sheet before your label goes to print.

Why does molecular weight matter in a topical PDRN formula?

Because PDRN is a large molecule and skin is a barrier. PDRN is a mixture of DNA fragments with chain lengths reported in the region of 80 to 2200 base pairs and molecular weights in the range of roughly 50 to 1500 kDa – enormous next to the actives formulators usually worry about delivering. It is the reason low-molecular-weight grades exist and the reason the delivery system in a topical PDRN product is not a detail. When you are comparing two raw materials, the molecular weight distribution tells you more than the headline percentage does.

What claims can a topical PDRN product make?

Cosmetic ones, about appearance. A topical PDRN product sold as a cosmetic in the United States can speak to how skin looks and feels – firmer-looking, smoother, plumper, more radiant. It cannot claim to heal, regenerate or repair tissue, and that is precisely the language the injectable PDRN literature is written in, which is what makes this ingredient a compliance trap. Wound healing and tissue regeneration are drug claims. Keep the claim set cosmetic and keep the substantiation attached to the finished product, not to the raw material’s reputation.

Is PDRN manufacturing done under certified GMP?

Yes. Moe’s Group holds ISO 22716:2007 for cosmetics Good Manufacturing Practices, with skin care, hair care and oils named in the certified scope, alongside ISO 9001:2015 and ISO 45001:2018, and operates an FDA registered facility. Certificates are downloadable on our certifications page.

The short version

• In stock: salmon PDRN and rose PDRN, formulated in house in California.
• Vegan line: rose PDRN – the only clear-cut call in the category.
• Evidence-led positioning: salmon PDRN – but the strong human data is injectable, not topical.
• Do not transfer plant evidence between sources. Ginseng data is not rose data.
• Look for sodium DNA on the ingredient list, and confirm the INCI on the spec before printing a label.
• Keep claims cosmetic. Healing and regeneration are drug language.

Start a PDRN product

Tell us the source, the format and the volume you have in mind, and our chemists will come back with options. Salmon PDRN and rose PDRN are in stock, with ginseng, rice and green tea PDRN available on request. Related reading: our announcement that PDRN is in stock for private-label brands, the full salmon PDRN vs rose PDRN comparison, and our peptide skincare contract manufacturing page if you are weighing polynucleotides alongside peptides. Certifications and FDA facility registration are documented on the certifications page. To talk through a formula, use the product inquiry form.